Opportunity Information: Apply for PAR 18 261
The Transition to Independent Environmental Health Research (TIEHR) Career Transition Award (K01, Clinical Trial Required) is a National Institutes of Health (NIH) career development grant designed as a three-year "bridge" program for newly independent faculty who are building long-term research careers in environmental health sciences. The core purpose is to help early-stage investigators strengthen their scientific direction, expand their expertise, and generate the kind of preliminary data and track record that positions them to successfully compete for independent environmental health research funding by the end of the award period. In other words, this K01 is structured to support the transition from early faculty independence into a stable, externally funded research program in environmental health.
This funding opportunity is listed under NIH Funding Opportunity Number PAR-18-261 and falls within the environment and health activity area (CFDA 93.113). It is offered as a discretionary grant mechanism, meaning it is not an entitlement program and awards depend on merit review and available funds. While the notice indicates an original closing date of 2021-05-07, applicants would normally need to verify whether the announcement is still active, has been reissued, or has been replaced by a newer FOA before preparing an application, since NIH opportunities are often updated over time.
The award is explicitly labeled "Clinical Trial Required," which is an important detail for project planning. This designation signals that the proposed research and training plan is expected to include a clinical trial component as NIH defines it. Practically, that means the application must be prepared using NIH clinical trial policies and the required clinical trial-related application elements, and the candidate should be prepared to address trial design, oversight, milestones, and protections for human participants (when applicable). It also implies that the applicant and mentors (or the candidate's advisory team) should have the appropriate clinical research and trial management expertise to carry out the proposed work in compliance with NIH expectations.
Eligibility, as summarized in the opportunity description, focuses on U.S.-based organizations and a range of higher education and nonprofit entities. Eligible applicant organizations include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both 501(c)(3) and non-501(c)(3) nonprofits) that are not institutions of higher education, as well as other eligible entities listed by NIH. The FOA also calls out several institution types as other eligible applicants, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and other similar organizations that meet NIH requirements.
At the same time, the opportunity makes clear that foreign institutions are not eligible to apply as applicant organizations. Non-domestic (non-U.S.) components of U.S. organizations are also not eligible to apply. However, "foreign components" as defined under the NIH Grants Policy Statement are allowed, which generally means certain scientifically justified project elements may be conducted outside the U.S. under an eligible U.S. applicant organization, provided NIH policy requirements are met and the foreign component is clearly described, justified, and appropriately overseen.
Overall, the TIEHR K01 is best understood as a structured, time-limited career development award aimed at newly independent faculty who want to cement their trajectory in environmental health sciences through mentored-to-independent development, targeted research progress, and the production of competitive outputs (such as publications, pilot findings, and grant-ready projects). The expected endpoint is not just completion of a project, but clear evidence that the investigator is prepared to secure subsequent, independent environmental health research funding. For the precise eligibility rules, required application components, budget and effort expectations, and the clinical trial requirements, applicants are directed to consult the full FOA text and the NIH Grants Policy Statement definitions referenced in the announcement.Apply for PAR 18 261
- The National Institutes of Health in the environment, health sector is offering a public funding opportunity titled "Transition to Independent Environmental Health Research (TIEHR) Career Transition Award (K01 Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113.
- This funding opportunity was created on 2017-11-08.
- Applicants must submit their applications by 2021-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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Apply for PAR 18 261
Applicants also applied for:
Applicants who have applied for this opportunity (PAR 18 261) also looked into and applied for these:
| Funding Opportunity |
|---|
| Transition to Independent Environmental Health Research (TIEHR) Career Transition Award (K01 Clinical Trial Not Allowed) Apply for PAR 18 291 Funding Number: PAR 18 291 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| The Role of the Microbiome in the Developmental Origins of Health and Disease (DOHaD) (R01 Clinical Trial Not Allowed) Apply for RFA ES 18 005 Funding Number: RFA ES 18 005 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $400,000 |
| Revolutionizing Innovative, Visionary Environmental health Research (RIVER) (R35 Clinical Trial Not Allowed) Apply for RFA ES 18 004 Funding Number: RFA ES 18 004 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $600,000 |
| SBIR E-learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed) Apply for RFA ES 18 006 Funding Number: RFA ES 18 006 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $100,000 |
| Exposure Analysis Services for the Environmental Influences on Child Health Outcomes (ECHO) Program (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 783 Funding Number: PA 18 783 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Novel Approaches for Characterizing Exposure and Response to Engineered Nanomaterials (R43 Clinical Trials Not Allowed) Apply for RFA ES 18 008 Funding Number: RFA ES 18 008 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43)(Clinical Trial Optional) Apply for PAR 18 901 Funding Number: PAR 18 901 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Telomeres as Sentinels of Environmental Exposures, Psychosocial Stress, and Disease Susceptibility: A Methods Comparison Study (U01 Clinical Trial Optional) Apply for RFA AG 19 023 Funding Number: RFA AG 19 023 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $200,000 |
| Research Network on Telomeres as Sentinels of Environmental Exposures, Psychosocial Stress, and Disease Susceptibility (U24 Clinical Trial Not Allowed) Apply for RFA AG 19 022 Funding Number: RFA AG 19 022 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $345,000 |
| Human Health Exposure Analysis Resource: Data Repository, Analysis and Science Center (U2C Clinical Trial Not Allowed) Apply for RFA ES 18 014 Funding Number: RFA ES 18 014 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $1,700,000 |
| Human Health Exposure Analysis Resource: Coordinating Center (U24 Clinical Trial Not Allowed) Apply for RFA ES 18 010 Funding Number: RFA ES 18 010 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $700,000 |
| Human Health Exposure Analysis Resource: UnTargeted Exposure Analysis Laboratories (U2C Clinical Trial Not Allowed) Apply for RFA ES 18 012 Funding Number: RFA ES 18 012 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $1,500,000 |
| Human Health Exposure Analysis Resource: Targeted Exposure Analysis Laboratories (U2C Clinical Trial Not Allowed) Apply for RFA ES 18 011 Funding Number: RFA ES 18 011 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $1,500,000 |
| Human Health Exposure Analysis Resource: Environmental Exposure Analysis Laboratories (U2C Clinical Trial Not Allowed) Apply for RFA ES 18 013 Funding Number: RFA ES 18 013 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $700,000 |
| Maintain and Enrich Resource Infrastructure for Existing Environmental Epidemiology Cohorts (R24 Clinical Trial Not Allowed) Apply for RFA ES 18 009 Funding Number: RFA ES 18 009 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $250,000 |
| Virtual Consortium for Translational/Transdisciplinary Environmental Research (ViCTER) (R01 Clinical Trial Optional) Apply for RFA ES 18 007 Funding Number: RFA ES 18 007 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $400,000 |
| Enhancing Data Management and Sharing in NIEHS-Funded Research Grants (Admin Supp Clinical Trial Not Allowed) Apply for PA 19 025 Funding Number: PA 19 025 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $75,000 |
| Early Screening for Autism Spectrum Disorder (R01 Clinical Trial Not Allowed) Apply for RFA MH 19 120 Funding Number: RFA MH 19 120 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $500,000 |
| Immuno-Oncology Translation Network (IOTN): Cancer Immunoprevention Research Projects (U01 Clinical Trial Not Allowed) Apply for RFA CA 19 014 Funding Number: RFA CA 19 014 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $500,000 |
| Immuno-Oncology Translation Network (IOTN): Cancer Immunotherapy Research Projects (U01 Clinical Trial Not Allowed) Apply for RFA CA 19 015 Funding Number: RFA CA 19 015 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $500,000 |
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